Assistant Professor

burleson

Department of Biology
University of the Incarnate Word
4301 Broadway
San Antonio, TX 78209
Work Phone: (210) 805-2544
Email: mburleso@uiwtx.edu

Education

2004-2008

B.S. in Biology Texas A&M University, College Station TX

  • Overall GPA 3.87
  • Science GPA 3.94

2009-2013

Ph.D. in Genetics/Molecular Biology UTSouthwestern Medical Center, Dallas TX

  • Molecular biology department
  • Genetics & Development Program
  • Overall GPA 3.4

Teaching Experience

2005-2006

Aggie Access Mentor, Texas A&M University, College Station TX

  • Teaching/Mentoring incoming freshmen

2006-2007

Chemistry Tutor, Texas A&M University, College Station, TX

  • Introductory chemistry tutor

2011

Guest experimental design lecturer for first-year graduate students

2011-2012

Workshop leader for high school students through the STARS program

2011-2013

Mentor in Dr. Rueyling Lin laboratory

  • 2011 – Rotation student (Steven)
  • 2012 – High School student (Elizabeth)
  • 2012-2013 – Master’s student (Tejas)
  • 2013 – Rotation student (Ebony)

2015

Mentor in Dr. Thomas Boyer laboratory

  • 2015 – Rotation student (Liesl)
  • 2015 – Rotation student (Alex)

2015

Individual Development Plan presenter at Cellular and Structural Biology retreat, the University of Texas Health Science Center at San Antonio

2015

Obtained Certificate of Completion for University Teaching Excellence Course, the University of Texas Health Science Center at San Antonio

2016

Adjunct Faculty - University of the Incarnate Word

  • Course: BIOL1402 – General Biology I for majors

2016

Cooperative Learning Workshops – University of the Incarnate Word

2017

Guest lecturer for UIW School of Osteopathic Medicine Masters of Biomedical Science Program – Molecular Biology

2016-2018

Center for teaching and learning workshops – University of the Incarnate Word

2016-2018

Visiting Assistant Professor of Biology – University of the Incarnate Word

Courses taught Fall 2016:

  • BIOL1402: General Biology I for majors
  • BIOL2122: Anatomy & Physiology Lab II
  • BIOL3202: Research Methods in Cell & Molecular Genetics
  • BIOL3411L: Cell Biology Lab
  • Courses taught in Spring 2017:
  • BIOL1402: General Biology I for majors
  • BIOL3202: Research Methods in Cell & Molecular Genetics
  • BIOL4399: Cancer Biology ( NEWLY DEVELOPED COURSE)
  • Courses taught Summer 2017:
  • BIOL1402: General Biology I for majors
  • BIOL3202: Research Methods in Cell & Molecular Genetics

Courses taught Fall 2017:

  • BIOL4370/6370: Molecular Biology ( GRADUATE COURSE)
  • BIOL6399: Cancer Biology ( GRADUATE COURSE)
  • BIOL2474L: Microbiology Lab
  • Courses taught in Spring 2018:
  • BIOL1402: General Biology I for majors
  • BIOL1403: General Biology II for majors
  • BIOL3202: Research Methods in Cell & Molecular Genetics

Courses taught Fall 2018:

  • BIOL1402: General Biology I for majors
  • BIOL 2474L: Microbiology Lab
  • BIOL 3361: Genetics
  • BIOL 4399: Cancer Biology

Research Experience

2008-2009

Research Technician, UTsouthwestern Medical Center, Dallas TX

  • Dr. Rueyling Lin laboratory
  • Investigate molecular mechanisms of A-P polarity establishment during embryogenesis using Caenorhabditis elegans.

2009

Research Rotation, UTsouthwestern Medical Center, Dallas TX

  • Dr. Leon Avery and Dr. Young-Jai You
  • Utilization of laser ablation technology in Caenorhabditis elegans to study satiety quiescence behavior upon nutritional intake.

2009

Research Rotation, UTsouthwestern Medical Center, Dallas TX

  • Dr. Michael Buszczak
  • Investigate stem cell maintenance and differentiation in Drosophila Melanogaster ovaries.

2010

Research Rotation, UTsouthwestern Medical Center, Dallas, TX

  • Michelle Tallquist
  • Determine underlying mechanisms for the epithelial to mesynchemal transition in the epicardium of the mouse heart.

2009-2013

Graduate Student, UTsouthwestern medical Center, Dallas TX

  • Dr. Rueyling Lin laboratory
  • Dissertation: Post-transcriptional regulation of maternally provided mRNA shapes early Caenorhabditis elegans embryogenesis.

2014-2016

Postdoctoral Researcher, Univ. of Texas Health Science Center, San Antonio TX

  • Dr. Thomas G. Boyer Laboratory
  • Elucidate SPOP-mediated GLI3-dependent SHH signaling in androgen independent prostate cancer AND characterize the MED12/CycC interface as a transducer of oncogenic Wnt/b-catenin signaling in colorectal cancer.

2017

Independent Investigator, University of the Incarnate Word

  • Mentored 3 undergraduate students for independent research studies
  • Investigate SPOP-mediated oncogenic signaling in cancer

Academic Awards and Honors

2004

Valedictorian first year tuition exemption (Texas A&M University)

2008

Magna Cum Laude (Texas A&M University)

2011-2013

Institutional National Research Service Award (NRSA): T32 predoctoral training grant, Genetics Training Program (T32GM083831); PI: John Abrams

2012

Nominated for Philanthropic Educational Organization (P.E.O.) Scholar Award

2014-2016

Institutional National Research Service Award (NRSA): T32 postdoctoral training grant, Cancer Biology Training Program (5T32CA148724); PI: Luzhe Sun

2015

First Place Postdoctoral Fellow Award Winner Poster session; 2015 Annual Terry M. Mikiten Research Forum

2015

Best Poster Presentation by a Postdoctoral Trainee; 2015 Joint Annual Retreat NCI T32/CPRIT Training Programs

2015

Third Place Postdoctoral Poster Presentation Winner; 2015 Cancer Therapy and Research Center Annual Symposium

2016

Individual National Research Service Award (NRSA): F32 postdoctoral fellowship (1F32CA200209); Deferred due to mentor’s funding

Community Service

2005-2008

Active member of Alpha Phi Omega – National Co-ed Community Service Fraternity

  • 50+ hours of community service per semester in projects including: Habitat for Humanity, Hospice, Christmas in the Park, Beach/park clean-up, etc.
  • Pledge group leader for 2 semesters

2011-2012

Laboratory tour guide for high school students through the STARS program

2016-2017

Science Fair Judge

  • John Jay Science and Engineering Fair
  • Alamo Regional Science and Engineering Fair

2017

Interviewer for the University of the Incarnate Word School of Osteopathic Medicine Medical School Multiple-Mini Interviews

2017

University of the Incarnate Word Meet the Mission

  • Helped organize and distribute Hurricane Harvey donations

2018

University of the Incarnate Word Meet the Mission

Professional Memberships

2005-2008

Alpha Phi Omega (National Co-ed Community Service Fraternity)

2012-2014

Genetics Society of America (GSA)

2013-2015

Society for Developmental Biology (SDB)

2014-2016

2016-2018

American Society for Cell Biology (ASCB)

Texas Academy of Science (TAS)

Conferences Attended

Graduate School :

  • 18 th International C. elegans Meeting
  • Los Angeles, California

ORAL PRESENTATION

  • C. elegans Development, Cell Biol. & Gene Express. Meeting Madison, Wisconsin

POSTER PRESENTATION

  • Model Organisms to Human Genetics Meeting - Washington D.C.

POSTER PRESENTATION

  • 19 th International C. elegans Meeting - Los Angeles, California

ORAL PRESENTATION

Postdoctoral

2014 Cancer Therapy and Research Center Symposium

San Antonio, Texas

POSTER PRESENTATION

  • The 2014 American Society of Cell Biology Meeting - Philadelphia, Pennsylvania

POSTER PRESENTATION

  • Mikiten Research Forum - San Antonio, Texas

POSTER PRESENTATION

  • Third Annual San Antonio Postdoctoral Research Forum - San Antonio, Texas

POSTER PRESENTATION

  • The 2015 American Society of Cell Biology Meeting - San Diego, California

POSTER PRESENTATION

  • 2015 Cancer Therapy and Research Center Symposium - San Antonio, Texas

POSTER PRESENTATION

Independent investigator WITH UNDERGRADUATE STUDENTS

  • 10 th Annual UIW Research Week - San Antonio, Texas

POSTER PRESENTATION

·By: Everardo Ramirez

  • Texas Academy of Science Meeting - Belton, Texas

POSTER PRESENTATION

· By: Everardo Ramirez

  • UTSA College Of Sciences Research Conference - San Antonio, Texas

POSTER PRESENTATION

· By: Mary Cogdell

Publications:

Peer Reviewed Publications :

Oldenbroek M, Robertson SM, Guven-Ozkan T, Gore S, Nishi Y, Lin R. Multiple RNA-binding proteins function combinatorially to control the soma-restricted expression pattern of the E3 ligase subunit   ZIF-1. Developmental Biology. 363(2), 388-398. PMCID: 22265679. 2012

Gallagher T, Kim J, Oldenbroek M, Kerr R, You YJ. ASI Regulates Satiety Quiescence in C. elegans. J Neuroscience. 33(23), 9716-9724. PMCID: 3726252. 2013

Oldenbroek M, Robertson SM, Guven-Ozkan T, Spike C, Greenstein D, Lin R. Regulation of maternal Wnt mRNA translation in C. elegans embryos. Development. 140(22), 4614-4623. PMCID: 3817945. 2013

Spike C, Coetzee D, Nishi Y, Guven-Ozkan T, Oldenbroek M, Yamamoto I, Lin R, Greenstein D. Translational control of the oogenic program by components of OMA ribonucleoprotein particles in Caenorhabditis elegans. Genetics. 198(4), 1513-1533. PMCID: 4256769. 2014

Oldenbroek M*, Clark AD*, Boyer TG. Mediator kinase module and human tumorigenesis. Crit. Reviews in Biochem. and Mol. Biol. 50(5), 393-526. 2015. PMCID: 4928375

  • Co-first author
  • Robertson SM, Medina J, Oldenbroek M, Lin R. Reciprocal signaling by Wnt and Notch specifies a muscle precursor in the C. Elegans embryo. Development. 144(3) 419-429 . 2016

Oldenbroek M. The emerging roles of SPOP in oncogenic signaling. Review. In preparation. 2018

Clark AD, Oldenbroek M, Spaeth JM, Boyer TG. Mediator kinase module is a transducer of oncogenic Wnt/Beta-catenin signaling. In preparation. 2018

Oldenbroek M, Boyer TG. Functional interaction between GLI3 and androgen receptor drives castration resistance in SPOP mutant prostate cancer. In preparation. 2018

Abstracts :

Oldenbroek M, Guven-Ozkan T, Robertson SM, Gore S, Lin R. A positive feedback loop involving translational repression and protein degradation maintains totipotency of germline blastomeres. 18 th International C. Elegans Meeting, Los Angeles, California. 2011 ORAL

Oldenbroek M, Robertson SM, Guven-Ozkan T, Lin R. Post-transcriptional regulation of maternally-supplied Wnt ligand during early embryogenesis . C. elegans Development, Cell Biology & Gene Expression Meeting. Madison, Wisconsin. 2012 POSTER

Oldenbroek M, Robertson SM, Guven-Ozkan T, Lin R. Post-transcriptional regulation of maternally-supplied Wnt ligand during early embryogenesis in C. elegans. Model Organisms to Human Genetics Meeting. Washington D.C. 2012 POSTER

Oldenbroek M, Robertson SR, Guven-Ozkan T, Spike C, Greenstein D, Lin R. Regulation of maternal Wnt mRNA translation in C. elegans embryos reveals mechanistic parallels between 3’ UTRs and transcription enhancers. 19th International C. Elegans Meeting, Los Angeles, California. 2013 ORAL

Oldenbroek M, Deng J, Sun L, Boyer TG. Prostate cancer-associated mutations in SPOP Stabilize GLI3, a critical determinant of androgen-independent prostate cancer cell growth. Joint Annual NCI T32/CPRIT retreat, San Antonio, Texas. 2014 POSTER