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University of the Incarnate Word
4301 Broadway, CPO #99
San Antonio, TX 78209-6397
Associate Professor, Pharmaceutical Sciences
Dr. Marcos A. Oliveira is originally from Brazil where he received his undergraduate in Physics. He received his Ph.D. in Structural Biology from Purdue University, where his work contributed to the development of novel antiviral agents. He began his career in Pharmacy as a faculty member at the University of Kentucky, College of Pharmacy. In 2006 he joined the team of Dr. Arcelia Johnson-Fannin in building a new School of Pharmacy at the University of the Incarnate Word. He is an author of over forty scientific manuscripts in peer reviewed journals, and holds two patents. He has received funding from the American Cancer Society, Kentucky Lung Cancer Research Program and NIH. He is currently working on the development of novel antibacterial agents in collaboration with biotech companies. In 2010 he was selected by Aetna along with a group of 12 health professionals as examples of Latino contemporary role models.
A more detailed Biosketch can be found @ http://myprofile.cos.com/mao
Research projects focus on: Education: Developing novel educational methods that focus on translational research (From bench to bedside). Drug Discovery: Our overall goal is the investigation of a novel mechanism of biofilm regulation involving polyamines and the identification of novel targets for drug discovery.In collaboration with Dr. Robert Perry and Jackeline Fetherston we are investigating the function of polyamines in Yersinia pestis (Plague) to develop novel biodefense agents. In collaboration with Dr. Patrick Woster we are working to identify small molecular weight compounds that interfere with polyamine metabolism in bacteria In collaboration with Dr. John Hart UTHSC-San Antonio we are working on the structural Biology of polyamine metabolism using structure-based-drug design approach to identify novel antibiotics. In collaboration with Dr. Peter Dube at UTHSC-San Antonio (Microbiology Dept.) we are testing the efficacy of polyamine anologues in an animal model of plague. In collaboration with Dr. Mary Pat Moyer we are translating our discoveries into novel therapeutics.